江涛 / 博士 研究员 博士生导师
国家“杰出青年基金”获得者 滚球app官网下载,十大滚球体育app，生物大分子全国重点实验室，研究组长
研究方向：利用结构生物学手段研究生物大分子的三维结构与疾病关系并开展药物研发
电子邮件：tjiang@ibp.ac.cn
电 话：010-64888510
通讯地址：北京市朝阳区大屯路15号（100101）
英文版个人网页：http://english.ibp.cas.cn/sourcedb/rck/EN_xsszmH_K/202005/t20200519_341404.html
简历
1987 - 1991 ?厦门大学化学系，获学士学位
1995 - 1998 ?滚球app官网下载,十大滚球体育app，获博士学位
1999 - 2004 ?滚球app官网下载,十大滚球体育app，副研究员
2004 - 至今 ??滚球app官网下载,十大滚球体育app，研究员
获奖及荣誉
2009年?入选“新世纪百千万人才工程”
2010年?获第三届“谈家桢生命科学创新奖”
2010年?获得国家自然科学基金委员会“国家杰出青年科学基金”十大滚球体育app资助
2011年?获得政府特殊津贴
2015年?获得“朱李月华优秀教师”奖
社会任职
承担十大滚球体育app情况
1. 神经退行性疾病的结构与功能研究以及药物研发。
2. 基因编辑工具的开发以及疾病监测应用。
3. DNA损伤应对的结构与功能研究及其病理意义探究。
4. 天然产物活性小分子的合成代谢相关酶的研究。
1. Huo YG*, Zhao HS, Dong QH, Jiang T*. (2023)?Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector. Nat. Microbiol. 8, 522-532.
2. Li HL, Huo YG, He X, Yao LP, Zhang H, Cui YQ, Xiao HJ, Xie WX, Zhang DJ, Wang Y, Zhang S, Tu HX, Cheng YW, Guo YS, Cao XT, Zhu YF, Jiang T, Guo XJ*, Qin Y*, Sha JH*. (2022) A male germ-cell-specific ribosome controls male fertility. Nature. 612(7941):725-731.
3. Xiao YM, Chen JY, Hou XC, Wang HW, Zhang KD, Xu SJ, Jiang T, Huo YG*, Zhang FY*, Gu LC*. (2025) A NanoLock-enabled, Craspase-based strategy for highly sensitive RNA detection. Nucleic Acids Res. 53(17): gkaf907.
4. Tong YR, Ma XL, Hu TY, Chen K, Cui GH, Su P, Xu HF, Gao W*, Jiang T*, Huang LQ*. (2022) Structural and mechanisticinsights intothe precise product synthesis by a bifunctional miltiradiene synthase. Plant Biotechnol J. 21(1):165-175.
5. Huo YG, Li T, Wang N, Dong QH, Wang XX, Jiang T*. (2018) Cryo-EM structure of Type III-A CRISPR effector complex. Cell Res. 28(12):1195-1197.
6. Xu M, Yang X, Yang XA, Zhou L, Liu TZ, Fan Z*, Jiang T*. (2016) Structural insights into the regulatory mechanism of the Pseudomonas aeruginosa YfiBNR system. Protein Cell. 7 (6):403-16.
7. Wang TY, Sun HL, Cheng F, Zhang XE, Bi LJ*, Jiang T*. (2013) Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5'exonuclease. Nucleic Acids Res. 41 (15): 7556-7565.
8. Tong Q, Wang F, Zhou HZ, Sun HL, Song H, Shu YY, Gong Y, Zhang WT, Cai TX, Yang FQ, Tang J, Jiang T*. (2012) Structural and functional insights into lipid-bound nerve growth factors. FASEB J. 26, 3811-3821.
9. Gong Y, Zhu D, Ding J, Dou CN, Ren X, Gu L, Jiang T*, Wang DC*. (2011) Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA. Nat Struct Mol Biol. 18, 1297-1299.
10. Tang L, Bai L, Wang WH, Jiang T*. (2010) Crystal structure of the carnitine transporter and insights into the antiport mechanism. Nat Struct Mol Biol. 17, 492-496.
11. Xu M, Bai L, Gong Y, Xie W, Hang HY*, Jiang T*. (2009) Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex. J Biol Chem. 284, 20457-20461.
12. Gong Y, Cao P, Yu HJ, Jiang T*. (2008) Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex. Nature. 454, 789-793.
13. Tang L, Li MH, Cao P, Wang F, Chang WR, Bach S, Reinhardt J, Ferandin Y, Galons H, Wan Y, Gray N, Meijer L, Jiang T*, Liang DC*. (2005) Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives. J Biol Chem. 280, 31220-31229.
14. Li MH, Kwok F, Chang WR, Lau CK, Zhang JP, Lo SC, Jiang T*, Liang DC*. (2002) Crystal structure of brain pyridoxal kinase, a novel member of the ribokinase superfamily. J Biol Chem. 277, 46385-46390.
?
（资料来源：江涛研究员，2025-11-20）
?
工作人员
研究生
离职人员
毕业学生